The company's suite of technologies is designed to cut out paperwork and increase participation in clinical trials.
ClinOne, a mobile tech company that manages clinical research, illustrated this week how their technology may be able to augment enrollment for clinical studies.
In a statement from the company, they claimed a 93% increase in enrollment in a US-based rescue study. The numbers were confirmed by the study’s global sponsor. Across 87 sites participating, only one was not using the technology after initial deployment. The system generated over 25,000 automatic notifications across all site-users in a 6-month period. Using a video-capable notification system as opposed to a group of traveling
ClinOne, which began rebranding itself from ClinTrialApp earlier this year, also reported a successful uptick in enrollment in a pharma-sponsored trial in June. Within a month of deploying, enrollment was up 41% in that trial. The technology was brought in due to low-enrollment in the first 12 months of the trial.
The platform is designed to use mobile technology to “centralize research and deliver the needed clinical trial content to the right participants,” and “improve day-to-day engagement of clinicians, academic researchers, drug developers, and patients,” in order to improve clinical trials.
Trials are a noteworthy field that mobile technology may be able to make a difference in, particularly multi-site trials. Oftentimes, patients simply lack awareness of their eligibility for a trial, or the parameters and connotations of a trial, leading to sluggish enrollment and mediocre retention. The hope of technology like ClinOne’s is to engage patients directly throughout the trial process, show them other trials they may be eligible for upon completion, and give them the ability to refer others they know who may be eligible.
On the researcher end, it provides a host of options for securely improving connectivity between study sponsors and research sites, offers real-time study progress updates, and digitizes much of the paperwork involved in clinical trials. The company claims its suite can better the process of screening prospective patients.
The structured approach differs greatly from the more audacious concept of an entirely remote study. Much fanfare surrounded the launch of Apple’s ResearchKit platform as itself a way to revolutionize clinical research, but in that sense studies were treated just like any other downloadable app and suffered the same retention problems that traditional clinical studies did. The ClinOne approach seems not to entirely discard the existing (literal) structures associated with running a clinical study, but instead to try to make the existing methods far more dynamic.
Currently, the company reports, its platform is in use in over 2,300 trials in 48 countries worldwide. According to a presentation, “Patients who understand the complete study value and message are far more likely to complete the study.”